The survival rate of liver metastases from rectal cancer is related to the patient’s physical condition, the number of liver metastases (whether they can be resected or not), whether they can tolerate high-intensity treatments and how they respond to the treatments; some studies claim that the 5-year overall survival rate of patients with surgically resectable liver metastases from colorectal cancer is 42% Liver is the primary organ for distant metastasis of colorectal cancer and is the main factor leading to death. Surgery remains an important treatment for patients with liver metastases from rectal cancer. Some studies claim that the 5-year overall survival rates of patients with surgically resectable and unresectable colorectal cancer liver metastases are 42% and 9%, respectively. When liver metastasis of colorectal cancer is diagnosed: ① If the systemic condition is poor and does not tolerate intense treatment, low toxicity chemotherapy regimen or optimal supportive therapy is recommended to improve the quality of life and maximize the survival time. After the systemic condition improves, whether the patient can tolerate other treatments should be evaluated again; ② If the patient can tolerate intense treatment, different treatment goals and individualized treatment plans should be formulated according to the classification of the disease. Overseas studies have shown that patients with liver metastases who do not receive treatment have a significantly poorer prognosis with less than 30% of patients surviving for 1 year and a 5-year survival rate of <5%. Domestic studies have claimed that the 5-year survival rate of colorectal cancer liver metastasis patients after hepatic metastases resection reached 45.0%, and the median survival period was 43 months. In conclusion, the survival rate of liver metastasis of colorectal cancer is related to many factors, so it is recommended to go to regular hospitals to comprehensively evaluate the condition and follow the doctor’s instructions to cooperate with the treatment in order to improve the patient’s prognosis and prolong the survival time, so as not to delay the condition.