Coronary heart disease is coronary atherosclerotic heart disease, the etiology has not been fully determined, is a multi-factor role in different aspects of the cause, the main risk factors are age and gender, dyslipidemia, hypertension, smoking and so on. 1. Age and gender: Mostly seen in middle-aged and old people over 40 years old, it progresses faster after 49 years old, and in recent years, there is a tendency for the clinical onset of age to be younger. The incidence rate of women is lower, because estrogen has anti-atherosclerotic effect, so the incidence rate of women increases rapidly after menopause. 2. Dyslipidemia: abnormal lipid metabolism is the most important risk factor for atherosclerosis. Coronary atherosclerotic heart disease is common in hypercholesterolemia. At present, the most certain is the atherogenic effect of LDL cholesterol. In addition, increased lipoprotein (a) may also be an independent risk factor. 3. Hypertension: The incidence of this disease is significantly higher in hypertensive patients, and the probability of developing coronary heart disease is three to four times higher. This may be due to endothelial cell damage in hypertension, which makes it easy for LDL cholesterol to enter the arterial wall and stimulate smooth muscle cell proliferation, causing atherosclerosis. 4. Other risk factors include: smoking, diabetes mellitus and glucose tolerance abnormalities, obesity, family history, long-term oral contraceptives, poor dietary habits are high-risk factors for this disease. Therefore, coronary heart disease, in the prevention and treatment also need to multi-factors, all-round prevention and control, on-time physical examination, usually maintain a good lifestyle, early prevention and treatment.