Whether kidney transplantation is possible after ten years of dialysis should be evaluated according to the patient’s status. If the patient has absolute contraindications to kidney transplantation, kidney transplantation is not recommended; if relative contraindications occur, they can be evaluated and re-judged by professional doctors. 1. Absolute contraindications to kidney transplantation: patients with untreated malignant tumors; active tuberculosis; active AIDS or hepatitis; drug addicts; progressive metabolic diseases; unstable patients with recent myocardial infarction; persistent coagulation disorders, such as hemophilia; life expectancy of less than 2 years; and other organs with serious dysfunctions. 2. Relative contraindications to renal transplantation: age >70 years; peripheral vascular disease; psychiatric related diseases; precancerous lesions; underlying diseases such as lipoprotein glomerulopathy, sickle cell disease, etc.; severe amyloidosis; combined with recurrent or difficult to control complicated urinary tract infections; and patients with donor/recipient cross-matched positive or PRA strong positive unprotected hypersensitivity uremic syndrome. Whether a patient can undergo kidney transplantation cannot be assessed by a single indicator, it is necessary to go to the hospital to do a comprehensive examination, according to the actual situation of the patient by the doctor to assess whether the operation is feasible.