Symptoms of advanced lung cancer include hoarseness, cough, sputum, fever, chest pain, shortness of breath, headache, bone pain and malignant fluid. 1. Symptoms of primary foci: In advanced lung cancer, if the laryngeal nerve is damaged, hoarseness will occur; cough is mainly irritating, with little sputum or a small amount of white sticky sputum, and blood sputum will easily appear; when it involves parietal pleura or directly invades the chest wall, it can lead to pain in the area; advanced lung cancer usually produces shortness of breath of different degrees. 2. Symptoms of metastasis: brain metastasis in advanced lung cancer may cause headache, dizziness, nausea and vomiting; if bone metastasis occurs, it may cause bone pain in the corresponding area; if liver metastasis occurs, it may cause loss of appetite and pain in liver area. 3. Systemic symptoms: patients with advanced stage of lung cancer often have poor general condition, which may be manifested as anemia, hypoproteinemia, emaciation, malignant fluid, obvious fatigue, etc. Patients with advanced stage of lung cancer should cooperate with doctors promptly. Patients with advanced lung cancer should cooperate with doctors for treatment in time in order to reduce patients’ pain, improve life quality and prolong survival period.