The generic name of POLIVI is clopidogrel bisulfate tablets, clopidogrel bisulfate tablets and aspirin which is better is not clear in the clinic, the mechanism of action of the two as well as the size of the resulting side effects are different, patients can be under the guidance of the doctor to choose according to their own situation. Clopidogrel bisulfate tablets and aspirin are both anti-platelet aggregation drugs. Clopidogrel bisulfate tablets inhibit ADP receptors by an adenosine diphosphate-mediated pathway; aspirin works by inhibiting platelet cyclooxygenase and blocking thromboxane A2 synthesis. Both drugs exert an inhibitory effect on platelet aggregation, preventing the formation of platelet thrombi. Aspirin may directly cause gastric mucosal damage and upper gastrointestinal bleeding, in contrast to clopidogrel bisulfate tablets, which cause less damage to the gastric mucosa and cause gastrointestinal reactions that are tolerated by most patients. Clopidogrel bisulfate tablets are often used after stenting or in more intense anti-platelet aggregation therapy, while aspirin is usually used in daily prophylaxis. If you are allergic to aspirin, you can also switch to clopidogrel bisulfate tablets. Therefore, patients can choose the suitable medication according to their own situation under the guidance of doctors.