The difference between folliculitis and genital herpes are different etiologic factors, different clinical manifestations, and different therapeutic drugs. 1. Different etiologic factors. Folliculitis is an inflammatory skin disease caused by bacterial and fungal infections, while genital herpes is a sexually transmitted disease caused by herpes simplex virus infection. 2. Different clinical manifestations. Folliculitis is initially manifested as red papules, gradually evolved into papular pustules, isolated scattered distribution, in a few cases will be fused with each other, can be accompanied by red, swelling, heat, pain and other inflammatory changes. Genital herpes is blister-like lesions, localized pain is obvious, blister rupture will form vesicles or ulcerated surface. The disease will recur and is contagious. 3. Different treatment drugs. Folliculitis is generally caused by bacterial or fungal infection, the treatment is divided into antibiotic treatment or antifungal treatment. If the bacterial infection can be topical mupirocin ointment, if the fungal infection can be topical ketoconazole ointment, if necessary, with oral medication. Genital herpes is caused by herpes simplex virus infection, need to carry out antiviral treatment, can be used externally or orally acyclovir and so on. Topical lidocaine hydrochloride ointment can be used for obvious pain. Folliculitis and genital herpes are two different diseases, it is recommended that patients go to a regular medical institution dermatology and venereal disease department, after diagnosis, follow the doctor’s instructions for drug treatment, avoid self-medication.