Baby syphilis 1:1 will turn negative in most cases after regular treatment. Infantile syphilis is usually congenital syphilis, which is caused by transplacental transmission of infection, and the clinical symptoms are emaciation, jaundice, skin and mucous membrane damage, fever, anemia, and nodular syphilis rash. Infantile syphilis 1:1 refers to the titer of syphilis non-specific antibody is 1:1, relatively low, in the early stages of the disease, indicating that infants and young children in the body of syphilis activity and infectiousness is not strong, if timely and regular treatment, in most cases, will be turned negative. Syphilis in infants and young children must be diagnosed and treated early, otherwise the condition will be further aggravated, and death may occur if the condition is serious.