Irregular vaginal bleeding is not necessarily due to a lack of progesterone, but can also be caused by ectopic pregnancy and bleeding during implantation. 1. Ectopic pregnancy: it is a common acute abdominal disease in obstetrics and gynecology, most commonly seen in tubal pregnancy, and can be life-threatening in severe cases. Typical clinical manifestations are history of menopause, lower abdominal pain on one side and irregular vaginal bleeding, which can be combined with ultrasonography, blood HCG (human chorionic gonadotropin) level, and posterior vaginal fornix puncture to assist in the diagnosis. 2. Bleeding during implantation: only seen in a small number of pregnant women, it is a small amount of irregular vaginal bleeding caused by localized damage to the endometrium during the implantation of the fertilized egg, which usually lasts for 3~4 days, and there may be slight pain in the lower abdomen, and the test of progesterone and blood HCG are normal, which usually does not need treatment and can disappear on its own. Clinically, when early pregnancy irregular vaginal bleeding need to go to the hospital in time, under the guidance of the doctor in order to clarify its specific causes, and give targeted treatment.