Generally, when the progesterone index of 20~25ng/mL is normal for pregnant women of advanced age, they should follow the doctor’s advice and observe. The value of progesterone after pregnancy will rise steadily with the increase of gestational weeks, and a sufficient amount of progesterone is beneficial to the embryo’s implantation and maintenance of pregnancy. Within 6 weeks of pregnancy progesterone is mainly secreted by the ovarian corpus luteum, and it is normal when the progesterone index is 20~25ng/mL after pregnancy in elderly pregnant women. However, when the progesterone level is low, it will increase the risk of miscarriage and requires active fertility preservation treatment as prescribed by the doctor. Pregnant women of advanced age have high-risk pregnancies, which increase the risk of abnormal fetal development, pregnancy complications, etc. They need to strengthen the management of pregnancy and strictly follow the doctor’s instructions for timely checkups, and undergo the appropriate screening tests in the early and middle trimesters of pregnancy, such as NT (fetal nuchal translucency) thickness measurements, prenatal diagnosis, and ultrasound for fetal structural screening, etc., in order to ensure the quality of the pregnancy.