Sedentary ankle swelling is usually a normal physiological phenomenon, but it may also be due to pregnancy, varicose veins of the lower limbs, kidney disease, liver disease and other factors. 1. Normal physiological phenomenon: when sitting, both lower limbs are in a low position, the venous return is reduced, and the tissue fluid in the lower limbs is increased, which will cause swelling of the ankles and wrists, and it is not accompanied by other discomforts, so you can raise both lower limbs and promote the blood return to alleviate the symptoms. 2. Pregnancy: After pregnancy, the uterus increases in size, which will compress the lower limbs and affect the blood circulation of the lower limbs, resulting in swelling of the ankles and wrists, and the symptoms can be aggravated by sitting for a long time. 3. Varicose veins of the lower limbs: due to the dysfunction of the lower limb venous valves, blood reflux occurs, making the blood stagnate in the veins of the lower limbs, resulting in swelling of the affected side of the ankles and wrists after a long period of sedentary life, and the affected side of the limbs can be seen as coarsened, twisted and raised superficial veins. 4. Kidney disease: such as nephritis, nephrotic syndrome, etc., due to kidney disease, resulting in reduced water and sodium discharge, resulting in sedentary, swollen ankles, morning, eyelids and facial edema. In addition, there are many other causes of sedentary ankle swelling, if accompanied by other discomforts, it is recommended to go to the hospital in a timely manner to identify the cause of the disease, and receive treatment as soon as possible.