Clinically, carotid mixed plaque is a more serious type of carotid atherosclerosis and belongs to unstable plaque. Mixed plaque that vascular ultrasound shows plaque echoes are not homogeneous, more than 20% of the echoes in the plaque are not consistent can be identified as uneven echo plaque, belongs to the unstable plaque, such as plaque dislodgement will cause distal vascular blockage, resulting in cerebral infarction. Carotid mixed plaque has a close relationship with ischemic cerebrovascular disease. Some researchers have found that unstable plaque rupture is an important cause of non-luminal cerebral infarction. For unstable carotid mixed plaques, it is clinically recommended to take lipid-lowering drugs such as atorvastatin and antiplatelet aggregation drugs such as aspirin and clopidogrel as prescribed by the doctor. It is recommended to consult a doctor in time and follow the doctor’s prescription. At the same time, pay attention to light diet, avoid greasy, maintain emotional stability, not too excited, regular review.