CA125 of 5.12u/ml does not require treatment, the normal value of CA125 is 0-35u/ml, which is in the normal range. CA125 refers to glycan antigen 125, a non-specific tumor marker, belongs to the examination of gynecological tumor markers, originates from the epithelial tissue of the fetal body cavity, and is commonly distributed in the mesothelial cell tissues in the normal population, and the normal value is 0-35u/ml, so it does not require treatment. CA125 has high sensitivity to many kinds of tumors, including ovarian cancer, liver cancer, lung cancer, colorectal cancer and other common tumors. CA125 is the most widely used ovarian epithelial tumor marker in the world, and it is widely used in the differential diagnosis of pelvic masses in clinical practice. CA125 of 5.12U/ml belongs to the normal range and does not require treatment. If you are not sure, you can have regular medical checkups in order to find out the abnormality in time.