Monkeypox can be treated. At present, there is no specific anti-monkeypox virus drug in China, therefore, once diagnosed with monkeypox, it is mainly controlled by symptomatic supportive treatment, complication treatment, etc. Chinese medicine can be tried. 1. Symptomatic supportive treatment: bed rest, strengthen nutrition, maintain water and electrolyte balance. If the body temperature is too high, antipyretic and analgesic drugs can be given to reduce fever, but attention should be paid to preventing profuse sweating to cause defecation. Do isolation protection according to the requirements. 2. Treatment of complications: For complications, such as secondary skin bacterial infections, effective antimicrobial drug treatment can be given, and the results need to be adjusted according to the culture, isolation and identification of pathogenic bacteria and drug sensitivity results. Prophylactic application of antibacterial drugs is not recommended. When encephalitis occurs, sedation, dehydration to lower the cranial pressure and airway protection are given. 3. Traditional Chinese medicine (TCM) treatment: According to the “Monkeypox Diagnostic and Treatment Guidelines (2022 Edition)”, TCM doctors recommend treating the disease by recognizing and treating the symptoms according to the principles of “examining the causes and treating the symptoms” and “three-cause systematic treatment”. Under the doctor’s guidance, symptoms can be relieved by taking Sheng Ma Ge Gen Tang, Zi Xue San, Xuan Bai Cheng Qi Tang, and so on. Once infected with monkeypox, you should actively cooperate with your doctor for treatment and take medication as prescribed by your doctor.