Acute T-lymphoblastic leukemia can be treated conservatively, but hematopoietic stem cell transplantation remains the fundamental treatment for leukemia. 15% of acute lymphoblastic leukemia belongs to acute T-type lymphoblastic leukemia, which can be treated with supportive therapy and chemotherapy. 1. Supportive therapy: for patients with severe anemia, suspension red blood cell transfusion can be given; for patients with severe thrombocytopenia, single platelet transfusion can be given; for patients with severe infection, levofloxacin can be given as anti-infection treatment. 2.Chemotherapy (1) Induction of remission treatment: programs such as vincristine + dexamethasone + cyclophosphamide + menthylase, until remission. (2) Consolidation therapy: drugs include cyclophosphamide, vincristine, doxorubicin and so on. (3) Maintenance therapy: such as giving drugs 6-mercaptopurine, methotrexate, vincristine, prednisone, etc. for maintenance therapy. The specific treatment program should be considered according to the patient’s condition, treatment effect, age and other factors. However, hematopoietic stem cell transplantation is still the fundamental method of treating acute leukemia. When the disease relapses several times, hematopoietic stem cell transplantation can be given in order to prolong the survival period. If acute T-lymphoblastic leukemia is diagnosed, patients are advised to go to the hospital in time and take regular treatment under the guidance of the doctor. The above drugs should be applied under the guidance of a doctor to avoid adverse reactions.