Psoriasis is an immune-mediated, chronic, relapsing, inflammatory, systemic disease induced by a combination of genetic and environmental effects. If you have psoriasis, you can use retinoids, immunosuppressants and biologics under the guidance of your doctor. 1. Vitamin A acid: such as oral avitamin A, which is mainly applied to plaque, pustular and erythrodermic psoriasis, and also can be used topically with vitamin A acid cream. 2. Immunosuppressants: immunosuppressants are mainly applied to moderate to severe plaque, erythrodermic, pustular and arthropathic psoriasis, and commonly used ones are methotrexate, cyclosporine and so on. 3. Biological agents: Biological agents are suitable for patients with moderate to severe psoriasis and/or psoriatic arthritis for whom conventional systemic therapy is ineffective or poorly tolerated. They include anti-TNF-α, anti-IL-12/23, anti-IL-17A monoclonal antibodies and monoclonal antibodies against IL-17A receptor. If you suffer from psoriasis, it is recommended to go to the hospital, clarify the cause of the disease, and standardize the treatment under the guidance of the doctor. Drugs need to be used in accordance with medical advice, do not self-medication.