Primary hypertension is mostly caused by heredity, irregular work and rest, etc. Commonly used drugs include calcium antagonists, angiotensin converting enzyme inhibitors, angiotensin receptor antagonists, diuretics, and beta-blockers. 1. Calcium antagonists: commonly used drugs include amlodipine and felodipine, etc., which are mainly applicable to elderly hypertension and simple systolic hypertension. Some patients may have adverse reactions such as dizziness and headache after taking them. 2. Angiotensin-converting enzyme inhibitors: commonly used drugs include captopril, ramipril, etc., which can be used to treat high blood pressure caused by diabetic nephropathy, metabolic syndrome and other diseases. Some patients may experience palpitations (rapid heartbeat, often accompanied by panic), tachycardia and other adverse reactions after taking them. 3. Angiotensin receptor antagonists: patients with a history of vascular disease with left ventricular hypertrophy, diabetic nephropathy, heart failure and other conditions can be treated with angiotensin receptor antagonists such as losartan. Some patients may experience adverse reactions such as palpitations (rapid heartbeat, often accompanied by panic) and tachycardia after taking them. 4. Diuretics: commonly used drugs include hydroflumethiazide, etc., which are mainly applicable to elderly patients with hypertension or simple systolic hypertension. Some patients may have adverse reactions such as nausea and vomiting after taking it. 5. β-blocker: commonly used drugs are metoprolol, bisoprolol, etc. It is mainly applicable to patients with arrhythmia and heart failure. Some patients may experience fatigue, headache and other adverse reactions after taking them. The specific use of drugs, it is recommended that patients under the guidance of the doctor, to avoid unauthorized medication on the body to cause adverse effects.