High alanine aminotransferase is generally indicative of hepatocellular damage, and any factor that causes hepatocellular damage may result in an abnormal elevation, and is an indicator of liver function. Elevated ALT is usually the result of liver injury, such as viral hepatitis, excessive alcohol consumption, medications, fatty liver, or cholestatic liver injury caused by poor bile drainage. Liver cell damage causes the release of intracellular ghrelin into the bloodstream, which leads to the elevation of this indicator. However, the exact cause of liver injury requires further blood tests and imaging tests. In addition to liver injury, other factors such as acute myocardial infarction, infectious factors, kidney disease, etc., can also cause cellular damage, leading to elevated ghrelin.