Swelling of the hand after running may be caused by physiological changes, or it may be caused by shoulder joint diseases, allergies, renal function diseases and other pathological reasons. 1. Physiological changes: because of the muscle fluttering state of the hand during the running process, the patient’s body fluids accumulate in the hand, which can cause swelling of the patient’s hand, which generally belongs to the physiological changes, and most of them will be restored after elevating the affected limbs. 2. Shoulder and elbow injuries: it is common for shoulder and elbow injuries to be caused by over-running, and the patient’s venous circulation is impaired, and the patient may have the symptom of swollen hands after running. 3. Allergy: Due to contact with certain allergic substances, such as pollen, etc., the patient’s hand skin is allergic to and swelling occurs. There may be other reasons for the swelling of hands after running, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or treatment.