Ground-glass nodules in lungs found in physical examination are serious if they are caused by malignant tumors such as lung cancer, while they are not serious if they are caused by benign diseases such as pneumonia and are treated in time. Ground-glass shadow or ground-glass nodule found on physical examination refers to the cloudy and slightly high density shadow on chest radiograph or CT, which may be caused by inflammation and other exudation in the lungs, or may be caused by invasion and infiltration of cancer cells of lung cancer. If it is caused by benign diseases such as pneumonia, tuberculosis, etc., it is not serious, and it can be improved and cured by taking anti-infection treatment such as ceftazidime and isoniazid. Most patients are asymptomatic due to physical examination, so they can be temporarily observed and regularly reviewed, and if there is no change in the review or the ground glass becomes smaller, then it is not serious. If it is caused by malignant tumors such as lung cancer, it will affect the survival and endanger the life, so it needs timely radical surgery, radiotherapy, chemotherapy, targeted therapy and other comprehensive treatments. The ground-glass shadow in the lungs found in physical examination should be analyzed according to the composition, size, shape and other preliminary benign and malignant risks, and it is recommended that the patient consults with a specialist and follows the doctor’s instructions for further examination and treatment.