Although Helicobacter pylori infection occurs in the stomach, the infection in the stomach can further affect the intestinal tract, such as indigestion and intestinal dysfunction. Helicobacter pylori is mainly parasitic in the human gastric mucosa and can tolerate gastric acid to survive. It is a kind of bacteria related to gastrointestinal diseases, which can cause peptic ulcer and chronic gastritis after infection, and it may further develop into gastric mucosa-related lymphoid tissue lymphoma and gastric cancer. The site of H. pylori infection is the gastric mucosa, so a series of upper gastrointestinal symptoms such as bloating, acid reflux, abdominal pain, nausea, loss of appetite, etc. can occur. When the gastric mucosa formed peptic ulcer, chronic inflammation, gastrointestinal digestive function is affected, so the intestinal digestion and absorption function can also appear obstacles and disorders. H. pylori infection not only affects the gastric flora, but also changes the distal intestinal flora, and the longer the duration of infection, the greater the difference in flora. When H. pylori infection occurs, it is recommended to go to a regular hospital for timely consultation and active treatment.