Urine protein quartet includes urinary immunoglobulin, urinary microalbumin, urinary NAG enzyme, and urinary beta2-microglobulin, which can be used to evaluate the kidney.
The first two of these are large molecule proteins and the last two are small molecule proteins. The presence of large molecule proteins in the urine generally indicates a problem with glomerular filtration, while the predominance of small molecule proteins can indicate a tubular reabsorption disorder.
Through the four urine protein tests, abnormalities in the measurement of urinary microalbumin and changes in globulin can be detected, which can be used to assess kidney disease and the presence of early glomerular damage.
Therefore, the four urine protein tests are of great clinical significance in observing the kidney condition. When abnormalities occur, the cause should be clarified by timely improvement of relevant examinations and treatment in accordance with medical advice.