The special antidote for organophosphorus pesticide poisoning is detoxification or chlorophosphidine. After organophosphorus pesticide poisoning, the patient’s muscles will be damaged because the organophosphorus pesticide can make acetylcholinesterase inactive, which will lead to muscle spasm and contraction, and in severe cases, respiratory muscle paralysis and death. The main function of antidotes for organophosphorus pesticide poisoning, such as detoxification and chlorophosphatidine, is to revive acetylcholinesterase, which can effectively prevent the destruction of muscles and can effectively relieve muscle spasm and respiratory muscle paralysis. For patients with severe organophosphorus pesticide poisoning, the use of atropine should be added to the use of the antidote, which can play a very good role in saving the patient’s life.