Blood in urine, difficulty in urination, frequent urination and swelling of lower limbs may be caused by acute glomerulonephritis, bladder cancer, ureteral stone, urinary tract infection and so on.
1. Acute glomerulonephritis: β-hemolytic streptococcus and other infections cause glomerular hemorrhage, exudation and other inflammatory lesions, and a large amount of inflammatory substances are deposited in the glomerulus, which leads to glomerular filtration obstruction, sodium and water retention and the above symptoms.
2. Bladder cancer: malignant lesion of bladder tissue leads to damage of normal tissue, necrosis of cancerous tissue, rupture of blood vessels, erosion and other changes leading to blood in urine, proliferation of cancerous tissue blocking the urethral orifice of bladder leading to urinary difficulty and frequent urination, prolonged inability of urination leading to hydronephrosis, renal dysfunction due to compression of renal parenchyma, water and sodium retention, and edema of lower limbs.
3. Ureteral stones: when ureteral stones are large in size, friction and irritation of the ureteral wall cause hematuria, in addition, the stones lead to ureteral obstruction, urine discharge is blocked causing hydronephrosis, and ultimately lead to renal dysfunction, so the above symptoms will occur.
4. Urinary tract infection: when bacterial, viral and other pathogens cause pyelonephritis, cystitis, urethritis and other infectious diseases of the urinary tract, the inflammatory reaction of the mucous membrane mucosa leads to hematuria.
In addition, the urethral mucosa is congested and edematous, and the urethra is narrowed accordingly, so it will be difficult to urinate and urinate frequently. Pyelonephritis leads to hydronephrosis, the renal parenchyma is compressed and water and sodium retention, so the lower limbs are swollen.
Blood in the urine, difficulty urinating, frequent urination, swelling of the lower limbs may be related to a variety of factors, it is recommended to consult a doctor for a clear diagnosis.