Blood pressure systolic blood pressure 160mmHg diastolic blood pressure 110mmHg belongs to the third level of hypertension, according to the patient’s specific situation to choose diuretics, β-receptor antagonists, calcium channel blockers, angiotensin-converting enzyme inhibitors, angiotensin II receptor antagonists. 1. Diuretics: such as amphotericin, furosemide, hydrochlorothiazide, etc., which are suitable for mild and moderate hypertension, and have strong antihypertensive effects on patients with simple systolic hypertension, salt-sensitive hypertension, combined obesity or diabetes mellitus. 2. β-receptor antagonists: such as propranolol, metoprolol, etc., are suitable for patients with different degrees of hypertension, especially for middle-aged and young patients with fast heart rate or patients with angina pectoris and chronic heart failure. 3. Calcium channel blockers: including nifedipine, verapamil, etc., which have better antihypertensive effect on elderly patients and alcoholic patients, and have anti-atherosclerotic effect in long-term treatment. 4. Angiotensin-converting enzyme inhibitors: such as captopril, enalapril, etc., especially for patients with heart failure, myocardial infarction, atrial fibrillation, proteinuria, diabetic nephropathy and so on. 5. Angiotensin II receptor antagonists: including chlorosartan, valsartan, etc., the antihypertensive effect is slow but durable and smooth, and there are fewer adverse reactions directly related to the drug. Patients should use drugs under the guidance of a doctor after consulting with him or her according to their personal situation and the effectiveness of the drug, and should not blindly use the drug on their own.