Long-term inhalation of budesonide does not usually cause damage to the airways, but it may cause side effects such as fungal infections. Budesonide is a locally inhaled glucocorticoid, and it is generally relatively safe to inhale budesonide through the airway. It can have an anti-inflammatory effect on the local airway, reduce airway hyperresponsiveness, and generally does not cause significant damage. And, because it is only localized glucocorticoids, the occurrence of systemic adverse reactions is also relatively small. Of course, if inhaled for a long period of time, some patients may experience some adverse effects, such as sore throat and fungal infections, as well as obesity, osteoporosis, damage to the gastric mucosa, and possibly diabetes. In order to reduce the side effects of topical inhaled glucocorticosteroids, one should pay attention to regular review and gargle about 10 minutes after inhaling glucocorticosteroids. Specific medications should be administered under medical supervision.