The side-effects of Chicken Nei Jin are not clear, but the elderly tend to be deficient in vital energy and weak in spleen and stomach, and long-term use may have disadvantages such as depletion of vital energy. However, the specific medication and course of treatment should be decided by a professional physician with evidence-based prescription. Chicken Neijin is the dried inner wall of the sand sac of the domestic chicken of the pheasant family. It is sweet in taste and flat in nature, and belongs to the spleen, stomach, small intestine and bladder meridians, with the effects of strengthening the stomach and eliminating food, astringing semen and stopping ejaculation (consolidating semen and preventing ejaculation), and clearing the gonorrhea and resolving stones. It is clinically used in the treatment of food stagnation, vomiting, diarrhea and dysentery, pediatric chancre (a chronic disease of children, manifesting as emaciation, abnormal diet, abdominal distension, thinning and yellowing of hair, etc.), enuresis, spermatorrhea, stonorrhea, and astringent pain (discharging gravel during urination or sudden interruption of urination, pain in urethra, intolerable pain in waist and abdomen), and so on. Caution should be exercised if there is deficiency of the spleen without accumulation and stagnation; the adverse effects of Chicken Nei Jin are not clear. When discomfort occurs, one should consult a doctor in time and choose medication under the guidance of physician’s diagnosis, and should not use medication on one’s own in order to avoid delaying the condition.