Si Shen Wan, Gui Su Di Huang Wan, and Hu Zi Li Zhong Wan are not recommended to be taken together. Si Shen Wan is composed of nutmeg, tonic oil, schizandra, Wu Wei Zi, Wu Zhu Zao, and jujube, which has the efficacy of warming the kidney, dispersing cold, astringing the intestines and stopping diarrhea and can be used for diarrhea caused by kidney yang insufficiency, with symptoms such as intestinal tinnitus and abdominal distention, loose bowel movements, poor diet, prolonged diarrhea, yellow face and cold limbs. Adverse reactions and contraindications are not clear. Gui Fu Di Huang Wan is composed of Cinnamon, Radix et Rhizoma Pinelliae, Radix Rehmanniae Praeparata, Cornu Cervi Pantotrichum, and Cornu Cervi Pantotrichum, with the effect of warming and tonifying Kidney-Yang, it can be used for the symptoms of cold pain in lumbar and knee caused by insufficiency of Kidney-Yang, dysuria, excessive sweating and coughing due to phlegm (a pathology product of the impaired metabolism of fluids). Adverse effects are not known. Contraindicated in pregnant women. This product is not suitable for people with Yin deficiency and internal heat. It should not be used in pregnant women, and should not be used in people with diarrhea with loose stools and burning in the anus. The effects of the three drugs have similarities, all can warm and tonify the kidney yang, dispersal of cold, at the same time the drug should not be taken to grasp the efficacy of the drug, it is not recommended to take the same drug. The discomfort, should be under the guidance of a doctor to take medication, not self-medication.