A common cause of perianal itching is eczema or a fungal infection. Eczema can be treated with topical glucocorticosteroids such as Denadyl cream, and fungal infections can be treated with topical antifungal emulsions such as terbinafine cream. Due to the moisture around the anus, breathability is poor, chronic inflammation stimulation is easy to induce eczema, do not pay attention to hygiene can also lead to fungal infections, or even eczema combined with fungal infections. Eczema and fungal infections have itchy manifestations. Fungal infections are commonly seen in ringworm, which is characterized by a ring of outwardly expanding erythematous plaques and possible flakes of skin. For fungal infections, topical terbinafine cream or ketoconazole cream is recommended and should be used under medical supervision. Eczema is characterized by erythema, papules, blisters, and oozing. Tissue microscopy does not reveal any fungus, and it can be treated with glucocorticoid creams such as Dinocaprolactone cream, Trimethoprim cream, etc. alone. Whether it is eczema or fungal infection, it is important to keep your underwear clean and change them frequently. When anal itching occurs, it is necessary to consult a doctor in time and under the guidance of a physician.