A small white spot in the middle of the eye is considered to be caused by keratitis or intraocular diseases. 1. Keratitis: this disease is mainly due to bacterial, viral, fungal and other pathogens infecting the cornea, patients often have eye pain, photophobia and other symptoms, the cornea inflammatory reaction occurs, resulting in patients appearing localized grayish-white corneal infiltration, which manifests itself in the middle of the eye with a small white spot. 2. Intraocular diseases: white reflection in the eye can be seen through the transparent cornea, which can be seen in cataract, uveitis, retinoblastoma and other diseases, which will have an impact on vision, and need to seek medical treatment in time to take surgical or medication to control the condition. Clinically, there are many reasons for a small white spot in the middle of the eye, and it is recommended that patients seek medical examination as soon as possible to clarify the specific causes.