Menstruation has not been coming to take progesterone to come, consider may be polycystic ovary syndrome, ovarian function decline, etc., this situation need to go to the hospital to do hormone six examination, ultrasound examination, anti-Müllerian tube hormone examination, etc., according to the specific circumstances can be oral ethinyl estradiol cyclopropylprogesterone tablets, estradiol valerate, dydrogesterone and other drugs treatment. 1. Hormone six examination: whether androgen is elevated, whether luteinizing hormone (LH) is high, whether luteinizing hormone (LH) than follicle-stimulating hormone (FSH) is more than 2.5~3 times. 2. Ultrasound: endometrial thickness, number of follicles, uterine size, etc. 3. Anti-Müllerian tube hormone examination: if it is lower than 2.0ng/ml, it will affect the follicle maturation; if it is lower than 1.1ng/ml, it means ovarian failure. Through the above checkups, it can be initially diagnosed whether it is caused by polycystic ovary syndrome or ovarian failure. If it is polycystic ovary syndrome, it is recommended to take oral medication such as ethinyl estradiol cyproterone tablets; if it is ovarian failure, it is recommended to take oral treatment with estradiol valerate and dextroprogesterone. If you have any discomfort symptoms, you need to clarify the cause of the disease under the guidance of your doctor, who will formulate an individualized diagnosis and treatment plan according to your specific condition, so as to avoid delaying your condition.