Normal people in need of growth hormone under the guidance of doctors, the bones will not be deformed. However, for some people who use drugs indiscriminately on their own, it may lead to bone deformation. Normal people will secrete growth hormone, which has the ability to promote the growth of bones, internal organs and the whole body. If the drug is used under the guidance of a doctor and regular medical checkups are conducted, and the dosage of the drug is adjusted according to the condition of the patient, then the bones will not be easily deformed. If the drug is used indiscriminately or the dosage is increased, bone deformation may be induced, such as acromegaly. For those who do not lack growth hormone and have normal bone development, but insist on taking growth hormone, bone deformation may also occur, such as osteoarthritic deformity, etc. For those whose epiphyses have completely closed, it is not easy for bone deformation to occur. For those who have completely closed epiphyses, are known to be allergic to growth hormone, or have active malignant tumors, growth hormone is contraindicated to prevent accidents. It is recommended to take growth hormone as prescribed by the doctor, and to communicate with the doctor promptly if any discomfort occurs after taking the drug.