Total bilirubin of 29.1 μmol/L is mildly elevated, and its severity depends on the etiology of the elevation. If it is caused by physiologic factors, it is generally not serious; if it is caused by pathologic factors, it suggests that the condition is more serious. 1. Physiological factors: most commonly seen after drinking alcohol, strenuous exercise, etc., causing physiological bile concentration, total bilirubin can be seen elevated in blood test, usually not accompanied by other indicators of abnormality. Usually there is no need to deal with it, and it can be recovered after the triggers are removed. 2. Pathologic factors: such as biliary obstruction, hepatitis, cirrhosis and other diseases. Generally, it can be accompanied by direct bilirubin or indirect bilirubin elevation, and clinically, jaundice, abdominal pain, fever and other manifestations may appear, which generally suggests that the condition has become serious, and should be treated in time. In conclusion, if the total bilirubin is 29.1μmol/L, you should go to the hospital in time to clarify the cause of the disease and receive treatment as soon as possible.