Popliteal cysts are very big not recommended to be eliminated blindly and quickly, different treatments need to be taken according to the specific situation, such as drug treatment, cyst puncture with drug treatment, arthroscopic surgery, traditional surgery and so on. 1. Drug therapy: for patients who are sensitive to drug therapy, oral glucocorticoid drugs such as hydrocortisone can be taken. 2. Cyst puncture with medication: the cyst fluid can be sucked out from the popliteal cyst by puncture and injected with drugs such as prednisolone to reduce the size of popliteal cyst. This method is mainly suitable for conservative treatment, and may recur after puncture. 3. Arthroscopic surgery: the popliteal cyst is removed under direct arthroscopic visualization, with low surgical risk and fast recovery. 4. Traditional surgery: if the above surgery is not easy to cut cleanly, surgical incision is feasible. If a popliteal cyst is diagnosed, early treatment is recommended to minimize the adverse effects of the disease. All of the above medications should be used under the guidance of a doctor to avoid self-medication.