Repeated itching of the scrotal skin aggravated at night may be due to scrotal eczema, scrotal inflammation and other diseases. 1. Scrotal eczema: it is a chronic, inflammatory, itchy skin disease that occurs in the scrotum area. Manifested as a polymorphic rash at the scrotum, intense itching, can be used glycerine lotion cleaning to reduce itching, external keratolytic agents such as salicylic acid ointment, glucocorticoids such as dexamethasone ointment and other treatments. 2. Scrotal inflammation: a common genitourinary infectious disease in men, is caused by pathogenic bacteria infection of the scrotum surface skin inflammation, mainly manifested in the scrotum at the skin redness, itching, itching is often intolerable, and even pain. It is recommended that patients go to a regular hospital for further examination to clarify the type of disease, and under the guidance of the doctor reasonable medication.