Slightly thickened adrenal glands, if the patient’s adrenal function is normal, without obvious discomfort symptoms, may not receive special treatment, usually pay attention to regular follow-up adrenal ultrasound, adrenal hormone examination, and so on. Slightly thickened adrenal gland is not a disease, it is just an imaging description, suggesting the manifestation of adrenal hyperplasia. It may be caused by a variety of diseases such as tumor, primary aldosteronism, primary hypoadrenocorticism, etc. It needs to be clearly diagnosed with clinical symptoms and other examination results. If the patient’s adrenal function is normal and there is no obvious discomfort, he/she may not receive any special treatment, but needs to be followed up regularly, and whether the adrenal morphology is abnormal through renal ultrasound and adrenal hormone examination, to make clear whether there is any abnormality of adrenal function. It is recommended that patients with slightly enlarged adrenal glands should seek medical treatment in time.