The difference between heart and spleen deficiency (weakness of the heart and spleen) and qi and blood deficiency lies in the etiology and clinical manifestations. 1. Etiology: Heart and spleen deficiency is mostly caused by excessive thinking, uncontrolled diet, or loss of nourishment due to prolonged illness. On the other hand, qi and blood deficiency is caused by the depletion of qi and blood due to prolonged illness, or qi deficiency over a long period of time, and insufficient biochemistry affects the blood, which may also be caused by blood deficiency over a long period of time. 2. Clinical manifestations: The manifestations of heart and spleen deficiency include heart-blood deficiency (heart-blood insufficiency) and spleen-qi deficiency, so there are palpitations (rapid heartbeat, often accompanied by panic), dizziness, forgetfulness, insomnia and dreaminess, as well as loss of appetite, abdominal distension, loose stools, yellowish color (yellowish color with no luster), fatigue (mental fatigue, physical fatigue), or a woman’s menstruation is small in volume and pale in color, and not complete, and so on. Weakness of qi and blood is manifested by pale or yellowish color, spontaneous sweating (involuntary sweating during the daytime, aggravated by sweating with a little movement), especially when moving, fatigue, emaciation, pale lips and mouth, dreaming, dizziness, and so on. If the patient is not feeling well, it is recommended to consult a doctor in time to find out the cause of the disease and standardize the treatment.