The pain of not being able to get up after twisting your back is considered to be caused by acute lumbar sprain, bone fracture, lumbar intervertebral disc injury, etc. General treatment, medication and surgical treatment can be taken according to the different causes of the disease. 1. Acute lumbar sprain: improper exercise can induce persistent muscle spasm, resulting in sudden pain in the lumbar region and inability to stand up. It is recommended that ice packs can be applied within 72 hours after the sprain; hot packs can be applied after 72 hours to relieve bruising and swelling; such as pain can be treated with oral non-steroidal anti-inflammatory drugs such as ibuprofen extended-release tablets, acetaminophen tablets, celecoxib capsules and other medications. 2. Fracture: If the patient is older and his waist is twisted, resulting in the inability to stand, it may be a fracture. It is recommended to take an X-ray in time to confirm the diagnosis. If there is a fracture, braking should be taken in time to ensure the relative stability of the fracture end and promote fracture healing. If the pain is severe, you can take oral analgesic drugs, such as tramadol hydrochloride extended-release tablets, aminopyralid tablets, oxycodone hydrochloride extended-release tablets and so on. 3. Lumbar intervertebral disc injury: lumbar intervertebral disc injury occurs after lumbar sprain, which will lead to the pain of not being able to get up, it is recommended to take bed rest, can also take local traction or reset massage and other methods of treatment. Combined with blood circulation and blood stasis medication, such as lumbar pain capsule, lumbar paralysis capsule, etc. for treatment. If the injury is severe, it can be treated with surgical incision of spinal canal decompression and internal fixation of pedicle root screws. The symptoms of lumbar sprain to the pain can not get up, should follow the doctor’s instructions to actively cooperate with the doctor’s treatment, do not self-medication, in order to avoid delaying the condition. The use of the above drugs need to follow the doctor’s advice.