Drinking and standing up with black eyes may be related to cerebral vasodilatation, sudden changes in body position, low blood sugar and other factors. 1. Cerebral vasodilatation: after drinking alcohol, alcohol will stimulate the cerebral blood vessels, resulting in cerebral vasodilatation, standing up by gravity, the blood drops rapidly, the brain temporarily blood supply is insufficient and the symptoms of black eyes. 2. Sudden change of body position: drinking has been sitting, stand up after the sudden change of body position, triggering postural hypotension, causing black eyes and other symptoms. 3. Hypoglycemia: After drinking, the blood absorbs a large amount of ethanol, which stimulates the pancreatic β-cells to secrete a large amount of insulin, triggering the symptoms of hypoglycemia, which leads to the blackening of the eyes when you drink and stand up. If you have a black eye after drinking, it is a temporary phenomenon, so you can sit or lie down to rest.