Hepatitis B minor triple yang playing interferon to turn negative, indicating that the condition has improved, and may even be cured. Usually interferon is a class of glycoprotein, mainly has the effect of anti-virus, inhibit cell proliferation and anti-tumor. If a patient with hepatitis B is negative after interferon injection, it means that the patient’s condition has improved and may be cured. Hepatitis B conversion can be categorized into 3 levels, which are hepatitis B virus DNA conversion, hepatitis B e antigen conversion and hepatitis B surface antigen conversion. Generally speaking, when acute hepatitis B patients have hepatitis B virus DNA turn negative, it means that the patients’ condition has improved and even can be completely cured. On the other hand, hepatitis B virus DNA conversion in chronic hepatitis B patients indicates that the immune function of the body has changed, which only means that the virus in the patient’s body is less. If hepatitis B e antigen turns negative, for acute hepatitis B patients, it means that the condition may be cured, while chronic hepatitis B indicates that the amount of virus is low. If the patient has hepatitis B surface antigen turn negative, and after treatment, the turn negative, you can stop the treatment, indicating that the patient’s condition has been cured. It is recommended that in the case of hepatitis B minor triple yang playing interferon to turn negative, under the guidance of the doctor to reasonably assess the condition.