Direct embryo transfer is generally not recommended for high TSH, and assisted reproduction techniques should be considered after treatment of the primary disease. TSH is thyrotropin, a hormone secreted by the pituitary gland that stimulates the thyroid gland to secrete thyroid hormone and stimulates the growth of thyroid follicular cells, which can lead to hyperthyroidism and thyroid hyperplasia. This indicator can be used to determine whether a patient has hyper- or hypothyroidism, as well as to understand the patient’s pituitary function. A high TSH is mostly indicative of hypothyroidism, so thyroid function must be adjusted before embryo transfer. Even if the embryo transfer is successful, hypothyroidism can be complicated by hypertension, placental abruption, spontaneous abortion, preterm labor, and low birth weight babies during pregnancy. In addition, because thyroid hormone is an important hormone to promote the development of the fetal nervous system, hypothyroidism affects the intellectual development of the fetus, which may lead to cretinism after birth. In order to avoid hypothyroidism affecting the development of the fetus, it is recommended that women who are preparing for pregnancy go to the hospital to have their thyroid function checked in a timely manner, and if they have hypothyroidism, they should follow the doctor’s instructions for treatment in a timely manner, so as to ensure that the fetus develops normally after embryo implantation and delivers the baby safely.