Low blood glucose after 2 hours of glucose tolerance may be hypoglycemia, which needs to be treated in accordance with the specific causes, including excessive weight loss or malnutrition, overdose of medication, adrenal hypofunction, pancreatic islet cell tumors and so on, and the corresponding treatments include strengthening nutrition, medication adjustments, and surgical treatments and so on. 1. Excessive weight loss or malnutrition: Excessive weight loss and prolonged malnutrition will cause low blood glucose, and it is necessary to pay attention to strengthening nutrition, and can eat more high-protein and high-carbohydrate food, which will be improved after dietary condition is improved. 2. Overdose: Diabetes can be caused by overdose of insulin or hypoglycemic drugs (metformin, etc.), adjust the medication under the guidance of the doctor. 3. Hypoadrenalism: Hypoadrenalism (congenital adrenal insufficiency, etc.) may also cause hypoglycemia, and exogenous supplementation of adrenocorticotropic hormone is possible. 4. Islet cell tumor: islet cell tumor is found through examination, because the excessive secretion of insulin will lead to hypoglycemia, and it can be removed radically through surgery. Low blood glucose after 2 hours of glucose tolerance, need to consult the hospital in time, after determining the specific cause of the disease in the clinician under the guidance of standardized treatment.