Skin scratching disorder, also known as artificial urticaria. Therapeutic drugs mainly include general treatment, antihistamines, drugs to reduce vascular permeability, immunosuppressants and so on. 1. General treatment: patients should avoid scratching, avoid rubbing the skin, wear cotton loose clothing, avoid wearing tight clothing or jewelry, etc.; acute stage can also be used externally with glycerite lotion to astringent, anti-itching effect. 2. Antihistamines: mainly including loratadine, levocetirizine hydrochloride, olopatadine hydrochloride, etc., can antagonize the role of histamine, play an anti-allergic, anti-itching effect. 3. Drugs to reduce vascular permeability: anti-allergy drug treatment, but also a combination of drugs to reduce vascular permeability, such as calcium gluconate, vitamin C and so on. 4. Immunosuppressants: commonly used immunosuppressant drugs include cyclosporine, etc., which has the effect of immunomodulation and needs to be used under the guidance of a doctor, and is suitable for patients with persistent artificial urticaria. In addition to immunosuppressants such as cyclosporine, patients can also use biologics, such as omalizumab, as prescribed by the doctor. It is recommended that patients with skin scratches go to the dermatology department of regular hospitals and hospitals in a timely manner, and standardize the treatment under the guidance of doctors.