Skin metastasis of lung adenocarcinoma is serious and its prognosis is worse than that of lung adenocarcinoma patients without skin metastasis. Skin metastasis of lung adenocarcinoma indicates that the tumor cells have spread and metastasized, which means the tumor is in the progressive stage and the disease has entered the advanced stage, and its prognosis is worse than lung adenocarcinoma without metastasis, and if no timely treatment measures are taken, the tumor can spread further in a short period of time and shorten the life span of the patients, so skin metastasis of lung adenocarcinoma is more serious. Therefore, skin metastasis of lung adenocarcinoma is more serious. After skin metastasis of lung adenocarcinoma occurs, surgery, radiotherapy, chemotherapy, targeted drugs and other comprehensive treatments are feasible to prolong the survival period and relieve the symptoms of patients, and local radiotherapy and cryotherapy are feasible to treat skin metastatic lesions. Patients with skin metastasis of lung adenocarcinoma should go to the hospital for consultation in time, and under the guidance and suggestion of doctors, standardized treatment is expected to alleviate the pain brought by the disease and prolong the survival period of patients.