Compound glycyrrhizin and diammonium glycyrrhizinate have different indications, contraindications, adverse reactions, etc., and should be used reasonably under the guidance of a professional physician, there is no such thing as a better drug. 1. Indications: Compound glycyrrhizin is suitable for the treatment of chronic liver disease, can also be used for the treatment of eczema and urticaria, while diammonium glycyrrhizinate is suitable for acute and chronic hepatitis, especially with elevated gammaglutaminase patients. 2. Contraindications: Compound glycyrrhizin is contraindicated for patients with aldosteronism, myopathy, hypokalemia, end-stage cirrhosis (such as elevated blood ammonia). Diammonium glycyrrhizinate is contraindicated in patients with hypokalemia, hypernatremia, hypertension, cardiac failure, renal failure, etc. 3. Adverse reactions: common adverse reactions of compound glycyrrhizin include hypokalemia, elevated blood pressure, sodium retention, etc.; common adverse reactions of diammonium glycyrrhizinate include headache, dizziness, palpitation and elevated blood pressure, itching of the skin. For the application of compound glycyrrhizin and diammonium glycyrrhizinate, it is recommended to consult a doctor in time and be guided by a professional doctor according to the individual situation.