If the child’s fever at night does not exceed 38.5 ℃, physical cooling methods can be used, if it reaches or exceeds 38.5 ℃ need to use drugs to reduce fever treatment. It is also important to treat the cause of the illness. Fever is a common symptom in childhood, for children with fever, the speed of temperature return to normal is related to the state of the disease and the choice of the correct antipyretic method. For children with fever at night but body temperature <38.5 ℃ can use warm water on the child's forehead, reduce the clothing worn and other physical methods of cooling, some children's body temperature can be gradually decreased; for children with body temperature ≥38.5 ℃ need to use antipyretic drugs such as ibuprofen, acetaminophen and other antipyretic treatments under the guidance of a doctor. At the same time for the cause of treatment is also very important for the recovery of body temperature, such as bacterial infection caused by respiratory tract infection, need to actively use antibacterial drugs such as cefaclor, cefdinir and other anti-infective treatment. In case of rheumatic immune diseases, immunosuppressants are needed for treatment. In case of hematological tumor-related diseases, chemotherapy, bone marrow transplantation and other treatments are needed. All of the above medications should be used under the guidance of a doctor and avoid self-medication. There are many other causes of nighttime fever in babies, and it is recommended that children with fever seek prompt medical attention and be evaluated and treated by a specialist.