If cholecystitis is not cured for a long time and repeated attacks, cancer may occur. Common cholecystitis combined with gallbladder stones and atrophic cholecystitis may cause cancer. 1. Cholecystitis combined with gallbladder stones: when cholecystitis is combined with gallbladder stones, due to the repeated stimulation of the mucous membrane of gallbladder wall by gallbladder stones, the gallbladder will be in a state of inflammation for a long period of time, which will lead to an increase in the probability of cancerous transformation of gallbladder. 2. Atrophic cholecystitis: atrophic cholecystitis refers to the repeated attacks of cholecystitis, which leads to the gradual inflammatory hyperplasia and fibrosis of gallbladder wall, and for a long time, it will prompt the gallbladder to gradually atrophy and lose the function of contraction and concentration of bile, and in serious cases, it will lead to cancerous transformation. If there is no obvious effect of conservative treatment for cholecystitis combined with gallbladder stones or atrophic cholecystitis, or if there are frequent recurrences, the gallbladder can be removed surgically to prevent cancer. When suffering from cholecystitis, you need to go to the hospital for examination and treatment in time to avoid delaying your condition.