Whether or not gallbladder wall roughness can heal on its own depends on the cause of the wall roughness. In this case, it can disappear gradually by adjusting the diet and abstaining from alcohol. However, the roughness of the gallbladder wall may also be caused by diseases such as cholecystitis, hepatitis or ascites, for example, the roughness of the gallbladder wall may appear in the early stage of cholecystitis, and the gallbladder wall will return to normal form after regular treatment and control. If chronic cholecystitis is formed, the gallbladder wall will not only become rough and thickened, but may also shrink or even calcify, resulting in irreversible lesions. In daily life, we should pay attention to the fact that we should have a physical examination every six months, and if we find that our gallbladder wall is hairy, we should seek medical attention in time, improve our lifestyle and diet, and develop regular and good eating habits.