Duodenal bulb ulcer is not Crohn’s disease, they are not the same disease. 1. Duodenal bulb ulcer: a common clinical peptic ulcer, mainly due to gastric acid, pepsin, Helicobacter pylori infection caused by the duodenal bulb mucous membrane produces ulcerative damage, the clinical symptoms are generally manifested as fasting or bedtime pain in the epigastric region, symptoms improve after meals, some patients are not obvious, duodenal bulb ulcers are generally not cancerous. 2. Crohn’s disease: Crohn’s disease is a kind of intestinal inflammatory disease with unknown cause, which can occur in any part of the digestive tract, and usually occurs in the terminal ileum and the right half of the colon, with segmental distribution. It is considered to be related to genetic, smoking and other factors, and the symptoms are mainly manifested as abdominal pain, diarrhea, intestinal obstruction, etc. It is incurable at present, and can be relieved through treatment. Therefore, duodenal bulb ulcer and Crohn’s disease are two different diseases, and it is recommended to be diagnosed by a doctor before treatment after the occurrence of abdominal pain and other uncomfortable symptoms.