Vitamin A cream removes melanin deposits. It reduces the formation of melanin, which reduces the pigmentation of the skin to achieve the removal of melanin. Vitamin A cream is able to affect melanin production in melanocytes and has an inhibitory effect on the activity of catalase type III, thus improving the skin’s melanization. However, when patients use retinoic acid, it is recommended that it be applied dabbed on and not over a large area. It is recommended that it be used before bedtime and away from light as much as possible. It is contraindicated for women who are breastfeeding and during the third trimester of pregnancy. When patients use Vitamin A cream appeared to be uncomfortable, it is recommended to go to the regular hospital for examination in a timely manner, under the guidance of professional doctors for standardized treatment.