The most common site of gout is the 1st metatarsophalangeal joint of the foot. Gout is a metabolic disease that causes inflammation of the joints and surrounding soft tissues, with common symptoms of redness, swelling, heat, and pain in the joints. Gout often occurs in the first metatarsophalangeal joint of the foot, but also in the ankle, knee, and other joints, and the reason why gout occurs more often in the 1st metatarsophalangeal joint is related to the location of the joint, the function of the joint, and other factors. As the 1st metatarsophalangeal joint is located at the end of the limb, there are relatively few blood vessels in the local tissues, and the slow blood flow makes it easier for uric acid to be deposited there. In addition, the 1st metatarsophalangeal joint is more susceptible to injury due to the high pressure it endures on a daily basis, and other factors that make this part of the body more susceptible to gout. It is recommended that gout patients go to the rheumatology and immunology department of a regular hospital for treatment.